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Gene expression profile at single cell level of whole melanoma tumor dissociations taken from sedentary or exercised mice

ABSTRACT: Gene expression profile at single cell level of whole melanoma tumor dissociations taken from sedentary or exercised mice

PROVIDER: PRJNA858777 | ENA |

REPOSITORIES: ENA

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Gene expression profile at single cell level of whole melanoma tumor dissociations taken from sedentary or exercised mice

Project description:Exercise reduces tumor growth in certain models but the mechanisms driving this is unknown. Tumors from sedentary or exercised mice were removed and processed for single cell sequencing to explore transcriptional changes in the tumor microenvironment induced by exercise.

2023-07-01 | GSE208205 | GEO

miRNA expression data from sedentary and exercised rats

Project description:Loss of skeletal muscle mass during aging, also known as sarcopenia, is a worldwide health problem. The etiology of sarcopenia remains unknown; however, recent studies revealed that sedentarism, fat gain, and epigenetic regulators such as miRNAs are critical regulators in its developing. One effective intervention to prevent and treat sarcopenia is aerobic exercise. We used miRNA microarrays to determine the changes in miRNA expression through time and the differences between sedentary and lifelong exercised rats.

2021-05-24 | GSE175390 | GEO

miRNA expression data from sedentary and exercised rats

Project description:miRNA expression data from sedentary and exercised rats

| PRJNA732210 | ENA

Single cell RNA sequencing of skeletal muscle endothelial cells in sedentary and exercised mice

Project description:Single cell RNA sequencing of skeletal muscle endothelial cells in sedentary and exercised mice

| PRJNA667253 | ENA

Transcription profiling of human skeletal muscle transcript from trained or sedentary young and old subjects

Project description:Aging is associated with mitochondrial dysfunction and insulin resistance. We conducted a study to determine the role of long-term vigorous endurance exercise on age-related changes in insulin sensitivity and various indices of mitochondrial functions. Experiment Overall Design: Skeletal muscle transcript profiling was done using Vastus Lateralis muscle biopsy samples from 10 young sedentary (YS), 10 older sedentary (OS), 10 young trained (YT) and 10 older trained (OT) men and women. Note that YT2, YS1, and OT1 didn't pass the Quality Control Step of dChip (high array/single outliers). Sedentary subjects exercised less than 30 min/day, twice per week. Trained subjects performed â¥ 1 hour cycling or running 6 days/week over the past 4 years.

2008-06-16 | E-GEOD-9103 | biostudies-arrayexpress

Aged Mouse Muscle and Serum: Sedentary or Exercised Animals with or without Nicotinamide N-methyltransferase Inhibitor Treatment

Project description:Aged Mouse Muscle and Serum: Sedentary or Exercised Animals with or without Nicotinamide N-methyltransferase Inhibitor Treatment

| PRJNA1113614 | ENA

Transcription profiling of heart tissue from rats that have undergone treadmill exercise or have been sedentary for different lengths of time

Project description:Seventy two rats were randomized to twelve independent groups of rats (n = 6 in all groups) where half of the rats were chosen for training (treadmill exercise training 1.5 hour 5 days a week, in 1, 4, 24, 48 days and for 4 and 8 weeks) or sedentary (no training) as described in detail by Wisloff et al. (Intensity-controlled treadmill running in rats: VO(2 max) and cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2001 Mar;280(3):H1301-10.) or Kemi et al.(Aerobic fitness is associated with cardiomyocyte contractile capacity and endothelial function in exercise training and detraining. Circulation. 2004 Jun 15;109(23):2897-904. Epub 2004 Jun 1.). The rats were scarified one hour after training (1, 4, 24 and 48 days) or 24 hours after training (4 and 8 weeks). Biopsies form left ventricle was taken form all rats and stored on -80°C for preparation of RNA. The same procedures were performed for the control/sedentary rats which were sacrificed at the same time as the exercised rats.

2006-11-10 | E-TABM-166 | biostudies-arrayexpress

Project description:PolG mtDNA Exercised and Sedentary

| PRJNA723420 | ENA

Gene expression analysis of hyper active mutant SPORTS rat [muscle]

Project description:To get insight into the genetic characteristics of hyper active mutant line of rat, SPORTS, and the effect of exercise on gene expression, we compared gene expression profiles of exercised SPORTS rat, sedentary SPORTS rat, and sedentary wild type rat. Using RNA extracted from the muscle of these rats, we performed microarray analysis. Subsequent GO analyses revealed that genes belonging to muscle development and glycolysis were upregulated in exercised SPORTS rat compared to sedentary SPORTS rat, and genes related to coagulation were upreguated in sedentary SPORTS rat compared to wild type rat. These results were consistent with phenotypes, such as hyper activity and thrombotic tendency, which were reported for SPORTS rat.

2018-11-01 | GSE88853 | GEO

Reducing Sedentary Behaviors Among Colorectal Cancer Survivors

Project description:Interview colorectal cancer survivors and use this input to create a brochure intended to guide reduction of sedentary behaviors in this population. Have colorectal cancer survivors review and comment on a draft of the brochure. A third group of colorectal cancer survivors will wear an Actigraph activity monitor for one week, then receive feedback on their activity level with the brochure. After one month this group will be surveyed by telephone regarding their use of the brochure, and their physical activity level.

| 2189898 | ecrin-mdr-crc

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