Project description:Schwann cells undergo reprogramming after nerve injury, switching to immature repair phenotype. The goal was to test what genetic perturbations are triggered in Schwann cells with the stimulus from melanoma cell secreted factors. We used microarrays to detail the changes in gene expression of Schwann cells treated with human melanoma conditioned medium.

2019-02-05 | GSE126040 | GEO

Gene expression changes induced by ILB in Schwann like cells

Project description:Gene expression changes induced by ILB in Schwann like cells

| PRJNA641711 | ENA

Effect of mechanical compression on gene expression in HEI-286 Schwann cells

Project description:In this study we present transcriptional changes in HEI-286 Schwann cells upon compression. Human HEI-286 Schwann cells were uncompressed, compressed at 5 μm height for 5 minutes or for 4 hours in 6-wells static confiner to monitor continuous molecular response to compression.

2026-05-30 | GSE292211 | GEO

Gene expression changes induced by ILB in Schwann like cells

Project description:To understand the mechanism of action of ILB we have used gene expression analysis to document the changes induced by the drug in Schwann like cells. Human Schwann-like cells (ATCC-CRL-2884) were treated with ILB (0.01 mg/ml) for 48 hours. Control samples were cultured parallel with no drug added. The expression data was used to identify the ILB-regulated genes.

2020-06-25 | GSE153199 | GEO

Genome-wide gene expression analysis of neurofibroma-derived NF1+/- and NF1-/- Schwann cells

Project description:Analysis of the effect of NF1 second hit mutation to the reading of the whole human genome by comparing the gene expression profiles of neurofibroma derived Schwann cell cultures representing two different NF1 genotypes (NF1+/- and NF1-/-).

2016-12-22 | GSE32029 | GEO

Effect of mechanical compression on gene expression in HEI-286 Schwann cells and pancreatic cancer cells MiaPaCa-2 and Panc01

Project description:Effect of mechanical compression on gene expression in HEI-286 Schwann cells and pancreatic cancer cells MiaPaCa-2 and Panc01

| PRJNA1237400 | ENA