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Expression profile of ATF2 knockdown in gastric cancer cell line MGC803 and genome-wide maps of ATF2 binding sites in gastric cancer cell line AGS

ABSTRACT: Expression profile of ATF2 knockdown in gastric cancer cell line MGC803 and genome-wide maps of ATF2 binding sites in gastric cancer cell line AGS

PROVIDER: PRJNA876738 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR21420290_1.fastq.gz	Fastqsanger.gz
	SRR21420290_2.fastq.gz	Fastqsanger.gz
	SRR21420291_1.fastq.gz	Fastqsanger.gz
	SRR21420291_2.fastq.gz	Fastqsanger.gz
	SRR21420292_1.fastq.gz	Fastqsanger.gz

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Expression profile of ATF2 knockdown in gastric cancer cell line MGC803 and genome-wide maps of ATF2 binding sites in gastric cancer cell line AGS [RNA-Seq]

Project description:Expression profile of ATF2 knockdown in gastric cancer cell line MGC803 and genome-wide maps of ATF2 binding sites in gastric cancer cell line AGS [RNA-Seq]

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Expression profile of ATF2 knockdown in gastric cancer cell line MGC803 and genome-wide maps of ATF2 binding sites in gastric cancer cell line AGS [ChIP-Seq]

Project description:Expression profile of ATF2 knockdown in gastric cancer cell line MGC803 and genome-wide maps of ATF2 binding sites in gastric cancer cell line AGS [ChIP-Seq]

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mRNA profiling of AGS gastric cancer cell line upon CTNNB1 silencing

Project description:Beta-catenin (CTNNB1) is a major component of Wnt signaling pathway and a crucial player in gastric cancer. To delineate the complex transcription program governed by CTNNB1 in gastric cancer cells, CTNNB1 was silenced in AGS, a commonly used Wnt signaling activated gastric cancer cell line and the resultant changes in genome-wide mRNA expression pattern was profiled using Affymetrix Human Gene 1.0 ST Array.

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Expression profile of ATF2 knockdown in gastric cancer cell line MGC803 and genome-wide maps of ATF2 binding sites in gastric cancer cell line AGS [RNA-Seq]

Project description:Activation transcription factor 2 (ATF2), a member of the ATF/CREB family of transcription factors, is implicated in a broad spectrum of cancer-related biological functions, such as cell proliferation, apoptosis and DNA repair. Growing evidence indicates ATF2 act as an oncogene or a tumor suppressor in different cancer types depending on its expression level and subcellular localization. In this study, RNA-seq and ChIP-seq were performed for identification of genome-wide DNA binding sites and potential transcription targets for ATF2.

2024-09-01 | GSE212684 | GEO

Expression profile of ATF2 knockdown in gastric cancer cell line MGC803 and genome-wide maps of ATF2 binding sites in gastric cancer cell line AGS [ChIP-Seq]

2024-09-01 | GSE212685 | GEO

Expression data of EBV-positive and EBV-negative subclones of gastric adenocarcinoma cell line AGS

Project description:Gastric cancer is one of the most common cancers worldwide. Epstein-Barr virus-associated gastric cancer accounts for approximately 10% of all gastric cancers. EBV expresses its own proteins and miRNAs (BART miRNAs) and regulates host gene expression. In this study, we examined the effect of EBV infection on host mRNA expression. Differential gene expression was analyzed between EBV-negative human gastric cancer cell line AGS and EBV-positive human gastric cancer cell line AGS-EBV.

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mRNA profiling in gastric cancer cell line AGS upon miR-25-3p silencing

Project description:Genome-wide mRNA expression profiling was performed in AGS, gastric cancer cell line, upon miR-25 silencing. At 48 hours upon anti-miR-25-3p (miRNA inhibitor) and non-targeting control RNA transfection, the whole transcriptome profiling was performed in triplicates. The miR-25 silencing elevates the diffuse gastric cancer features like expression of COL1A2, expression of COL1A2 co-expressed genes, Epithelial to Mesenchymal Transition (EMT) and angiogenesis associated genes.

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2021-01-06 | GSE124022 | GEO