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RNA sequencing on the PyMt cell line after culture with test versus control CD4+ T supernatants

ABSTRACT: RNA sequencing on the PyMt cell line after culture with test versus control CD4+ T supernatants

PROVIDER: PRJNA883594 | ENA |

REPOSITORIES: ENA

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RNA sequencing on the PyMt cell line after culture with test versus control CD4+ T supernatants

Project description:The antitumor immunity mediated by TSLP-stimulated CD4+ T cells in advanced breast cancer is mediated by the induction of a senescent-like phenotype in cancer cells.

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Consequences of Cyp2c44 deletion in the polyoma middle T (PyMT) breast cancer tumor proteome

Project description:Comparison of the proteome of intact primary breast cancer tumors from PyMT mice versus PyMTxCyp2c44-/- mice.

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Transcription profiling of mouse AKR/J x PyMT F1 versus DBA/2J x PyMT F1 tumors

Project description:F1 hybrids from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses display a 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms. Expression studies were performed to determine whether polymorphism-driven gene expression signatures predictive of outcome could be generated from mouse tumor tissues Experiment Overall Design: Mammary tumors from adult F1 animals from (AKR/J x PyMT) and (DBA/2J x PyMT) outcrosses was collected and arrayed on Affymetrics chip to identify basal differences in gene expression between the different genotypes

2009-01-13 | E-GEOD-13221 | biostudies-arrayexpress

Transcription profiling of mouse AKR/J x PyM F1 versus DBA/2J x PyMT tissues to investigate the effect of inherited polymorphism on prognostic gene expression signatures (super series)

Project description:This SuperSeries is composed of the following subset Series:; GSE13221: (AKR/J x PyMT)F1 versus (DBA/2J x PyMT)F1 tumor expression data; GSE13222: (AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 blood expression data; GSE13223: (AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 bone marrow expression data; GSE13224: (AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 lung expression data; GSE13225: (AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 spleen expression data; GSE13227: (AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 Thymus expression data; GSE13230: Met1 or DB7 tumor gene expression Experiment Overall Design: Refer to individual Series

2008-12-05 | E-GEOD-13231 | biostudies-arrayexpress

Arabidopsis seedling hydroponic treatment with Streptomyces AGN23 culture supernatants

Project description:Arabidopsis seedling hydroponic treatment with Streptomyces AGN23 culture supernatants

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Single cell RNA sequencing on PyMT mammary gland primary tumor and lung metastases

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Next generation sequencing of neutrophils from WT, PyMT and PyMT-Cxcr2-/- mice

Project description:We report the comparison of gene expression of neutrophils in the mammary gland of PyMT and PyMT-Cxcr2-/- animals as well as the one of WT bone marrow

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