Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of PGF2α on the transcriptome of the bovine corpus luteum

ABSTRACT: Effect of PGF2α on the transcriptome of the bovine corpus luteum

PROVIDER: PRJNA896629 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Effect of lactation and location relative to the corpus luteum on the transcriptome of the bovine oviduct epithelium

Project description:Lactation and associated metabolic stresses during the post-partum period have been shown to impair fertility in dairy cows. The oviduct plays key roles in embryo development and the establishment of pregnancy in cattle. The aim of this study was to investigate the effects of lactation and location relative to the corpus luteum (CL) on the transcriptome of the bovine oviduct epithelium.

2019-01-07 | GSE124110 | GEO

Effect of PGF2α on the transcriptome of the bovine corpus luteum

Project description:To investigate the rapid effects of PGF2α on the corpus luteum we performed gene expression profiling analysis using data obtained from RNA-seq of controls and treatments at two time points with 4 biological replicates/group .

2022-11-04 | GSE217053 | GEO

Prostaglandin F2α -induced changes in transcriptome of bovine mid cycle versus early corpus luteum

2010-07-31 | GSE23348 | GEO

Prostaglandin F2α -induced changes in transcriptome of bovine mid cycle versus early corpus luteum

Project description:Despite much investigation, mechanisms conferring stage specific responsiveness of the corpus luteum (CL) to prostaglandin F2 (PG) are unknown. The objective of this study was to identify PG- induced changes in transcriptome of bovine CL specific to d 11 ( PG responsive) but not d 4 (PG refractory) CL associated with luteolysis. CL were collected from heifers at 0, 4 and 24 h following PG injection on d 4 and 11 of the estrous cycle (n = 5 animals/treatment) and isolated RNA labeled and hybridized to Affymetrix GeneChip Bovine Genome Arrays. At 4 and 24 h post PG respectively, 221 (d 4) and 661 (d 11) and 248 (d 4) and 1419 (d 11) regulated genes were identified. Thirty Angus crossbred heifers were assigned to one of six treatments (n = 5 per treatment) in a 2 x 3 factorial arrangment, using a completely random design.Corpora lutea were collected at 0 (control), 4 or 24 h following injection of saline (control) or PG on d 4 or d 11 of the estrous cycle. Total RNA was isolated from luteal tissue. The isolated RNA was labeled and hybridized to Affymetrix GeneChip Bovine Genome Arrays.

2010-07-31 | E-GEOD-23348 | biostudies-arrayexpress

Transcriptomic profile of porcine corpus luteum after PPAR gamma ligands treatment

Project description:The corpus luteum plays a critical role in reproduction because it is the primary source of circulating progesterone. This study aimed to determine the in vitro effect of peroxisome proliferator-activated receptor gamma (PPARγ) ligands on the transcriptome genes expression in the porcine corpus luteum in the mid- and late-luteal phase of the estrous cycle using RNA-seq technology. The corpus luteum slices were incubated in vitro in the presence of PPARγ agonist – pioglitazone and antagonist—T0070907. We identified 40 differentially expressed genes after pioglitazone treatment and 40 after T0070907 treatment in the mid-luteal phase as well as 26 after pioglitazone and 29 after T0070907 treatment in late-luteal phase of the estrous cycle. In addition, we detected differences in genes expression between the mid- and late-luteal phase without treatment (409). These results should become a basis for further studies explaining the mechanism of PPARγ action in the reproductive system in pigs.

2022-11-15 | E-MTAB-11964 | biostudies-arrayexpress

microRNA dynamics in the bovine corpus luteum

Project description:The dynamics of microRNA transcriptome in the bovine corpus luteum during its formation, function and regression

| PRJEB20028 | ENA

Expression data from bovine corpus luteum treated with equine chorionic gonadotropin (eCG)

Project description:In order to indentify genes regulated by eCG, and involved in CL development and progesterone increases, the transcriptome was evaluated using the microarray technology Cows (Bos indicus) were divided into control, stimulated and superovulated groups. The stimulated group received 400 IU of eCG on day 8 and the superovulated group received 2000 IU of eCG on day 4 after the beginning of synchronization. Corpus luteum were collected at day 6 after ovulation e the trasncripitome was available by microarray.

2012-05-08 | E-GEOD-37844 | biostudies-arrayexpress

Effect of lactation and location relative to the corpus luteum on the transcriptome of the bovine oviduct epithelium

Project description:Effect of lactation and location relative to the corpus luteum on the transcriptome of the bovine oviduct epithelium

| PRJNA510799 | ENA

miRNAs in the porcine corpus luteum

Project description:miRNAs in the porcine corpus luteum

| PRJNA591167 | ENA

Gene expression profiles in the bovine corpus luteum (CL) of the estrous cycle and pregnancy: Possible roles of chemokines in regulating CL function during pregnancy

Project description:To determine functional differences between the corpus luteum (CL) of the estrous cycle and pregnancy in cows, gene expression profiles between the CL of the estrous cycle and pregnancy were investigated. A 15 K bovine oligo DNA microarray detected 138, 265 and 455 differentially expressed genes (>2-fold; P<0.05) in the bovine CL of 20-25, 40-45, and 150-160 days of pregnancy compared with 10-12 days of the estrous cycle. The different gene expression profiles may contribute to functional differences between the CL of pregnancy and the CL of the estrous cycle in cows. Chemokines including eotaxin and lymphotactin may regulate CL function during pregnancy.

2014-08-10 | GSE59770 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data