Project description:To investigate the function of A3B, we established 92.1 cell lines with A3B knocked down and MEL290 cell lines with A3B overexpression. We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cell lines with two replicates.

2023-06-07 | GSE218751 | GEO

Genes regulated by Hfq

Project description:Genes regulated by Hfq

| PRJNA882102 | ENA

genes regulated by mitoflash

Project description:genes regulated by mitoflash

| PRJEB10870 | ENA

Effect of overexpression of A3B and RNA editing calling in mouse tissues [WES]

Project description:To test if A3B has RNA editing activity we performed SNV calling from WES of 8 mouse livers (Samples 1-8) and 8 pancreas (Samples 7-16)

2023-07-25 | GSE209722 | GEO

Post-transcriptionally regulated genes are essential for pluripotent stem cell survival

Project description:Here, by combining transcriptome and proteome profiling, we identified 228 post-transcriptionally regulated genes with strict regulation at the protein level in PSCs. Among them, 84 genes were found necessary for the survival of several cell types including PSCs, and 20 genes were identified as specific for the survival of PSCs. These 20 proteins were upregulated only in PSCs and not in differentiated cells derived from the three germ layers. Subcellular fractionation of the mRNA showed that the expression level of most of the 20 proteins was regulated at the mRNA localization stage from the nucleus to the cytoplasm in PSCs, but their translation efficiency was unchanged compared with other cell types. Together, these results reveal a critical function of post-transcriptionally regulated genes on PSC survival.

2022-05-10 | PXD028489 | JPOST Repository

Identification of genes regulated by Bcl11b

Project description:Identification of genes regulated by Bcl11b

| PRJNA856979 | ENA

METTL3 regulated genes in HCC cell

Project description:METTL3 regulated genes in HCC cell

| PRJNA632566 | ENA