Project description:Transriptome of brown adipose tissues from E18, 4 and 10 days old, and 4 and 8 weeks old C57BL6/N mice were examined to describe the development of the tissue.
Project description:Gene expression profile from brown adipose tissues of Prdm16 knockout and wile type mice. Prdm16 is a transcription factor that regulates the thermogenic gene program in brown and beige adipocytes. However, whether Prdm16 is required for the development or physiological function of brown adipose tissue (BAT) in vivo has been unclear. By analyzing mice that selectively lacked Prdm16 in the brown adipose lineage, we found that Prdm16 was dispensable for embryonic BAT development.
Project description:Gene expression profile from brown adipose tissues of Prdm16 knockout and wile type mice. Prdm16 is a transcription factor that regulates the thermogenic gene program in brown and beige adipocytes. However, whether Prdm16 is required for the development or physiological function of brown adipose tissue (BAT) in vivo has been unclear. By analyzing mice that selectively lacked Prdm16 in the brown adipose lineage, we found that Prdm16 was dispensable for embryonic BAT development. Brown adipose tissues were collected from Prdm16 knockout and wiletype mice with 4 biological replicates per condition. Experiment was done in two separate batch for 6-week-old and 11-month-old. Extracted RNA was hybridized to Agilent two-color arrays.
Project description:This project includes proteomic data of brown adipose tissue from mice modeled with Cuprizone 300mg/Kg/Day for one month versus wild-type mice. CB represents the brown adipose tissue from wild type mice. MB represents the brown adipose tissue from mice treated with cuprizone.
Project description:The aim of this study was to identify genes expressed selectively in brown adipose tissue as compared to white adipose tissue from the same animals. This analysis provides a gene set that is brown and white adipose selective. Keywords: tissue comparison from mice
Project description:TIme course of gene expression changes in epididymal white adipose tissue of 3-4 month old male Bl6 mice treated with CL 316243 for 0,1,3 or 6 days Keywords: time-course