Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome profiling of lymph nodes from Spink5 conditional knock-out mice.

ABSTRACT: Transcriptome profiling of lymph nodes from Spink5 conditional knock-out mice.

PROVIDER: PRJNA930882 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR23323871_1.fastq.gz	Fastqsanger.gz
	SRR23323871_2.fastq.gz	Fastqsanger.gz
	SRR23323872_1.fastq.gz	Fastqsanger.gz
	SRR23323872_2.fastq.gz	Fastqsanger.gz
	SRR23323873_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 21

Similar Datasets

Transcriptome profiling of lymph nodes from Spink5 conditional knock-out mice.

Project description:We generated a viable mouse model of Netherton syndrome by conditional ablation of Spink5 gene in the epidermis. To study the systemic inflammation phenotype of this mouse model at the molecular level, we induced Spink5 deletion in the skin of young adult mice and collected inguinal lymph nodes for transcriptome analyses.

2024-02-05 | GSE224409 | GEO

Transcriptome analysis of tendon in Mkx conditional knock out mice

Project description:Transcriptome analysis of tendon in Mkx conditional knock out mice

| PRJNA1193985 | ENA

scRNAseq of stromal cells isolated from mesenteric lymph nodes (MLN), peripheral lymph nodes (PLN) and mandibular lymph nodes (mandLN)

Project description:scRNAseq of stromal cells isolated from mesenteric lymph nodes (MLN), peripheral lymph nodes (PLN) and mandibular lymph nodes (mandLN)

2022-09-01 | E-MTAB-11644 | biostudies-arrayexpress

scRNAseq of stromal cells isolated from mesenteric lymph nodes (MLN), peripheral lymph nodes (PLN) and mandibular lymph nodes (mandLN)

Project description:scRNAseq of stromal cells isolated from mesenteric lymph nodes (MLN), peripheral lymph nodes (PLN) and mandibular lymph nodes (mandLN)

| PRJEB52336 | ENA

RNA-sequence of epithelial-specific Yap conditional knock out mouse lung

Project description:RNA-sequence of epithelial-specific Yap conditional knock out mouse lung

| PRJNA523998 | ENA

m6A-sequencing of Mettl14-conditional knock-out retinas and matched control.

Project description:m6A-sequencing of Mettl14-conditional knock-out retinas and matched control.

| PRJNA848799 | ENA

Transcriptome profiling of lesional skin from Spink5 conditional knock-out mice

Project description:Transcriptome profiling of lesional skin from Spink5 conditional knock-out mice

| PRJNA930447 | ENA

Expression profile of conditional knock out of beta-catenin by K19-CRE at E7.5

Project description:expression profile of conditional knock out of beta-catenin by K19-CRE at E7.5. Tested a wild type with two alleles of beta-catenin, a heterzyote with one deleted allele and the conditional null in the domain on cytokeratin 19 driven CRE expression Keywords: other

2005-04-13 | GSE2519 | GEO

Gene expression in the pancreatic lymph node of Deaf1 knock out mice vs. BALB/c controls

Project description:A microarray study performed in the pancreatic lymph nodes of Deaf1 knock-out and BALB/c control mice to identify genes that are regulated by the transcriptional regulator Deaf1. These experiments constitute a portion of the study described below: Abstract: Type 1diabetes (T1D) can result from a breakdown in peripheral tolerance which is controlled by peripheral tissue antigen (PTA) expression in lymph nodes. Here, we identified a transcriptional regulator, deformed epidermal autoregulatory factor 1 (Deaf1), which regulates the expression of various PTAs in the pancreatic lymph node (PLN). We found, by microarray, that Deaf1 controls the expression of ~600 genes in the PLN. In the non-obese diabetic (NOD) mouse model of T1D, we identified a wild-type form of Deaf1 (DF1) and a truncated alternatively spliced variant (DF1-VAR1) that hetero-dimerizes with and decreases the transcriptional activity of DF1. The expression of DF1 correlates with the expression of various pancreatic PTAs such as insulin, and during the onset of destructive insulitis in NOD mice, DF1 expression is downregulated, while the DF1-VAR1 expression is upregulated in the PLN. A reduction in DF1-controlled PTA expression in the PLN, leading to decreased peripheral tolerance, could underlie the pathogenesis of NOD disease.

2009-07-15 | GSE13163 | GEO

Transcription profiling of mouse mesenteric, branchial and axilary lymph nodes from C57Bl/6 femails or CD27 knock out females

Project description:Mesenteric, brachial and axilary lymph nodes from 4 C57Bl/6 females or 5 CD27KO females, both groups were 6 weeks old, were extracted. The different lymph nodes were pooled and a single cell suspension was created. The cell suspension from WT or CD27KO mice was stained with anti-TCRd-PE (GL3) and anti-CD3e-PE Cy7 (2C-11), and FACSorted for double-positive cells on a BD Aria, obtaining around 1 million cells of each sample. These cells were spun down and the pellet was frozen in liquid nitrogen and kept at -80 ÂºC before RNA extraction.

2008-12-01 | E-NCMF-23 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data