Project description:We investigated daily oscillations in salivary miRNA and microbial RNA to explore relationships between these components of the gut-brain-axis and their implications in human health. Nine subjects provided 120 saliva samples at designated times, on repeated days. Samples were divided into three sets for exploration and cross-validation. Identification and quantification of host miRNA and microbial RNA was performed using next generation sequencing. Eleven miRNAs and 11 microbial RNAs demonstrated consistent diurnal oscillation across the first 2 sample sets and accurately predicted collection time in the hold-out set based on multivariate logistic regression modeling. Associations among five circadian miRNAs and four circadian microbial RNAs were observed.
2018-07-06 | GSE116686 | GEO
Project description:Five Cardinium endosymbiont genomes in Brevipalpus mites
| PRJNA437437 | ENA
Project description:Five New Genomes of Indian Photorhabdus Isolates
| PRJNA434554 | ENA
Project description:complete mitochodrion genomes of five cyperaceae species
| PRJNA953783 | ENA
Project description:Five Cardinium endosymbiont genomes in Brevipalpus mites
Project description:This study aimed to identify differentially expressed long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs) in damaged cartilage (DC) and un-damaged cartilage (UDC) from osteoarthritis (OA) patients. RNA sequencing was performed on cartilage samples from five OA patients undergoing total knee arthroplasty. Bioinformatics analysis, including Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment, and competing endogenous RNA (ceRNA) network construction, was conducted.