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GATAD2B containing NuRD complex drives R-loop dependent chromatin boundary formation at double strand breaks

ABSTRACT: GATAD2B containing NuRD complex drives R-loop dependent chromatin boundary formation at double strand breaks

PROVIDER: PRJNA962190 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR24319271_1.fastq.gz	Fastqsanger.gz
	SRR24319271_2.fastq.gz	Fastqsanger.gz
	SRR24319272_1.fastq.gz	Fastqsanger.gz
	SRR24319272_2.fastq.gz	Fastqsanger.gz
	SRR24319273_1.fastq.gz	Fastqsanger.gz

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GATAD2B containing NuRD complex drives R-loop dependent chromatin boundary formation at double strand breaks

Project description:To understand how components of NuRD could be recruited to DNA double-stranded break sites, we generate site-specific DNA double strand breaks through an inducible endonuclease AsiSI-ER system by adding 4-OHT, we applied antibodies against GATAD2B and HDAC1, both of which are components of NuRD complex, to pero ChIP in either DMSO or 4OHT treatment condition.

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