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6 small intestinal macrophage subsets (CD4–Tim4–CD163–, CD4+Tim4–CD163–, CD4+Tim4+CD163–, CD4–Tim4–CD163+, CD4+Tim4–CD163+, CD4+Tim4+CD163+ ) from adult male C57BL/6J mice

ABSTRACT: 6 small intestinal macrophage subsets (CD4–Tim4–CD163–, CD4+Tim4–CD163–, CD4+Tim4+CD163–, CD4–Tim4–CD163+, CD4+Tim4–CD163+, CD4+Tim4+CD163+ ) from adult male C57BL/6J mice

PROVIDER: PRJNA973088 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR24600178_1.fastq.gz	Fastqsanger.gz
	SRR24600178_2.fastq.gz	Fastqsanger.gz
	SRR24600179_1.fastq.gz	Fastqsanger.gz
	SRR24600179_2.fastq.gz	Fastqsanger.gz
	SRR24600180_1.fastq.gz	Fastqsanger.gz

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6 small intestinal macrophage subsets (CD4–Tim4–CD163–, CD4+Tim4–CD163–, CD4+Tim4+CD163–, CD4–Tim4–CD163+, CD4+Tim4–CD163+, CD4+Tim4+CD163+ ) from adult male C57BL/6J mice

Project description:To better determine functional heterogenity of small intestinal macrophages, 6 subsets of were sorted for RNA sequencing based on expression of CD4, Tim4, and CD163

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Project Title: Proteome analysis of CD4+ T cell subsets

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Transcriptomic signatures of spleen and liver CD4+ T cells from Leishmania donovani-infected C57BL/6J mice

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CD4/CD25 subsets of mouse spleen

Project description:A comparison of CD4+CD25+ and CD4+CD25- splenic T cells. Although both subsets have regulatory T cell activity in an induced transplantation tolerance model, the CD4+CD25+ subsets are apparently 10 fold enriched in regulatory T cells. SAGE analysis is performed and compared both on resting and CD3 activated populations. Keywords: other

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Small intestinal epithelial cells from C57Bl/6J mice

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Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq

Project description:Innate lymphoid cell (ILC) subsets that mirror helper T cells in their effector cytokine profiles have recently emerged as central players in both homeostatic and inflammatory conditions. Like their Th1, Th2 and Th17/Th22 helper T cell counterparts, ILC subsets are categorized based on their expression of specific transcription factors and effector cytokines: group 1 ILC (ILC1) express T-bet and IFN-Î³; group 2 ILC (ILC2) express GATA-3 and type 2 effector cytokines such as IL-13 and IL-5; and group 3 ILC (ILC3) express RORgt and the cytokines IL-22 and/or IL-17. Under this nomenclature, natural killer (NK) cells and lymphoid tissue inducers (LTi) are considered ILC1 and ILC3, respectively. ILC1 contain both CD4+ and CD4- populations, but whether this phenotypic characteristic reflects functional differences between these two populations is unknown. These studies examine the gene expression profiles of CD4+ vs CD4- ILC1 in a cohort of healthy control subjects. ILC subsets were isolated from the peripheral blood of healthy control subjects. cDNA was isolated and amplified from sorted populations, and gene expression was analyzed by RNAseq

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Effect of STAT1 gain of function R274Q on gene expression in CD4+ T cells from STAT1 GOF/CMV Cre and wild type C57BL/6J control mice

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Cardiac left ventricles of 12 week-old male C57BL/6J and C57BL/6J-chrY<A/J/NaJ> mice

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Expression data of human tonsilar CD4 positive T cell subsets

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