Project description:Exp5 is a nuclear export factor in the animal miRNA biogenesis pathway. This experiment examined how reduced Exp5 levels affected miRNA expression profiles.
Project description:In this study, we proved the exercise-induced promotion of osteogenic differentiation and inhibition of adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) through establishing exercise animal model by treadmill running experiment. miRNA sequencing analysis identified 16 upregulated and 2 downregulated miRNAs in exercise group.
Project description:In this study, we proved the exercise-induced promotion of osteogenic differentiation and inhibition of adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) through establishing exercise animal model by treadmill running experiment. lncRNA sequencing analysis identified 44 upregulated lncRNAs and 39 downregulated lncRNAs in exercise group.
Project description:The present work emplyed pigs as an animal model for recognition of molecular processes associated with fat deposition. The Transposase-Accessible Chromatin signal changes dependent on fat content were showed at the liver levels. In the experiment Złotnicka White pigs were used that were not under selection pressure, because they are included in to National Preservation Program.
