Project description:The goal of this study was to determine the gene similarities and overlap between human HER2+ breast cancer cells treated with a HUNK inhibitor (HSL119) and samples engineered with HUNK shRNA (KD1 and KD2). A main objective was to determine if genes related to the AKT pathway were changed in HUNK treated or HUNK knockdown groups compared to control.
Project description:Dysfunctional epidermis increases dermis inflammation in systemic sclerosis: results from a novel epidermal equivalent engineered from SSc keratinocytes.