Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Detection of plant microRNAs in edible-plant based products

ABSTRACT: Detection of plant microRNAs in edible-plant based products

PROVIDER: PRJNA983220 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Detection of plant microRNAs in edible-plant based products

Project description:Plant-based diets could be a key source of microRNAs in animals. Plant microRNAs are cross-kingdom gene expression regulators that could modulate mammalian gene expression, influencing their physiology. Therefore, it is important to identify the microRNA expression profile of plant foods in order to identify potential target genes and biological functions in the mammalian host. Next-generation sequencing was applied to identify microRNAs in RNA samples derived from nuts (walnut and almond), vegetables (spinach) and fruits (orange, apple, olive, pear, and tomato). Our data revealed that edible plant contain a large number and diverse type of microRNAs.

2023-09-05 | GSE234786 | GEO

Identification of Exosome-Like Nanoparticle Derived MicroRNAs from Eleven Edible Plants

Project description:In this study, we found that the highly expressed miRNAs appear in EPDELNs (Edible plant-derived exosome-like nanoparticles) have the potential to regulate human mRNA in a cross-kingdom manner. Target prediction and functional analysis revealed that highly expressed miRNAs were closely associated with inflammatory responses and cancer-related pathways. Therefore, we hypothesized that miRNAs in EPDELNs may be a crucial factor behind the regulatory function of EPDELNs.

2018-06-25 | GSE116095 | GEO

Plant Viroid Detection Microarray

Project description:Plant Viroid Detection Microarray

| PRJNA189479 | ENA

Plant virus detection microarray

Project description:Plant virus detection microarray

| PRJNA116809 | ENA

Identification of Exosome-Like Nanoparticle Derived MicroRNAs from Eleven Edible Plants

Project description:Identification of Exosome-Like Nanoparticle Derived MicroRNAs from Eleven Edible Plants

| PRJNA477334 | ENA

Plant microRNAs in WT and SIDT1 KO mice liver

Project description:Animal microRNAs (which lack 2'-O-methyl modification) can be broken down at the terminal nucleotide by oxidation, while plant microRNAs (with 2'-O-methyl modification) are not affected. To gain additional sight into the role of SIDT1 in exogenous plant microRNAs absorption, we profiled oxidized smalll RNAs of liver from SIDT1 deficient mice and their wild type couterparts.

2020-10-19 | GSE132152 | GEO

Host cell protein detection in antibody drug products

Project description:Detection and quantitation of host cell proteins in six antibody drug products using data dependent acquisition LC-MS/MS

2024-08-10 | PXD053529 | Pride

Detection of plant microRNAs in EVOO and plasma samples of healthy volunteers 2 hours postingestion of 40 mL of EVOO.

Project description:NGS has been applied to microRNA-enriched RNA obtained from Extra Virgin Olive Oil (EVOO), beer and plasma samples of healthy volunteers that usually consume EVOO hours after the ingestion of 40 mL of EVOO. Results: We did not detect significant amount of microRNA in the EVOO samples. Plasma samples did not contain EVOO microRNAs nor other microRNAs from plant origin. Starting plant material was 30 mL of EVOO or a pool of plasma samples of 5 volunteers

2016-06-30 | E-GEOD-76735 | biostudies-arrayexpress

Detection of plant microRNAs in EVOO and plasma samples of healthy volunteers 2 hours postingestion of 40 mL of EVOO.

2016-06-30 | GSE76735 | GEO

Identification of exosome-like nanovesicle (ENV) associated miRNAs in edible plants

Project description:MicroRNAs (miRNAs) are small non-coding RNAs between 18-23nts in size which regulate the translation and stability of target mRNAs. miRNAs are present in dietary plants and are conventionally thought to be degraded during the gastrointestinal digestion process. Recent reports suggest that a few dietary microRNAs may exhibit resistance to this process, enter systemic circulation and exert biological effects on animal physiology, currently known as cross-kingdom regulation. However, such horizontal transfer of miRNAs via different kingdoms is highly likely for miRNAs that are present intrinsic extracellular vesicles which increases their bioavailability. These vesicular structures from plants are known as Exosome-like nanovesicles (ENV). ENVs have been isolated from several edible plants. ENV-derived miRNAs are probably more bioavailable and are spontaneously absorbed in intestinal epithelium to suppress target transcripts in human/microbial/viral kingdoms. Such cross-kingdom regulation exhibited by ENV-miRNAs, if properly investigated and validated, may aid in the development of non-toxic and cost-effective therapeutics to treat human diseases. In this line, we purified ENVs from four edible plants (Soy bean, ginger, amla and turmeric). Small RNA population from these ENVs were isolated and profiled through small RNA sequencing to identify ENV-associated miRNAs enriched in each species.

2024-10-13 | GSE246292 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data