Project description:The rabbits ingest the mother's droppings at the nest. This behaviour contributes to the transmission of the maternal microbiota to its progeny, it is involved in the maturation of the digestive ecosystem of the rabbits and reduces mortality. In view of these observations, it is possible to assume that the digestive system is involved. To support this hypothesis, gene expression is measured using an expression chip. The aim is to detect over- or under-expressed genes under certain conditions and to link them in particular to immunity.
Project description:Microarray analysis of white adipose tissue (WAT) and bone marrow adipose tissue (BMAT) from 22-week-old or 13-week-old male New Zealand White rabbits. From both cohorts, BMAT was sampled from the distal tibia (dBMAT) and the radius and ulna (ruBMAT), while WAT was sampled from the inguinal (iWAT) and gonadal (gWAT) depots. From the 13-week-old cohort, BMAT was also sampled from the proximal tibia (pBMAT). Sufficient RNA could not be isolated from all tissues for all rabbits, so for some rabbits only a subset of tissues is included.
Project description:We report RNA-seq data obtained on dissected aorta and four heart valves from rabbits fed with chow diet (n=7), cholesterol-rich diet (n=6) or lard-rich diet (n=7). Rabbits that received cardiac irradiation combined with the cholesterol-rich diet were also included (n=7).