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TranscriptomicsFunctional Connection with Cardiac Tissues Confers Maturation Phenotypes in hPSC-Derived PHOX2B::GFP Expressing Sympathetic Neurons
...derived from human pluripotent stem cells (hPSCs) are a remarkable tool for modeling human neural development and diseases. However, it remains largely unknown whether the hPSC-derived neurons can be functionally coupled with their target tissues in vitro, which is essential for understanding inter-c...
ORGANISM(S): Homo sapiens 
2016-07-01 | E-GEOD-80689 | biostudies-arrayexpress
0
TranscriptomicsGenomic landscape of meningiomas: genotyping
Meningiomas are one of the most common adult brain tumors. For most patients, surgical excision is curative. However, up to 20% recur. Currently, the molecular determinants predicting recurrence and malignant transformation are lacking. We performed global genetic and genomic analysis of 85 menin...
ORGANISM(S): Homo sapiens 
2011-10-11 | E-GEOD-16583 | biostudies-arrayexpress
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TranscriptomicsGenomic landscape of meningiomas: gene expression
Meningiomas are one of the most common adult brain tumors. For most patients, surgical excision is curative. However, up to 20% recur. Currently, the molecular determinants predicting recurrence and malignant transformation are lacking. We performed global genetic and genomic analysis of 85 menin...
ORGANISM(S): Homo sapiens 
2010-11-30 | E-GEOD-16581 | biostudies-arrayexpress
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GenomicsEvolutionary Genome Analysis of Transformation into Small Cell Carcinomas from Lung Adenocarcinomas
Anecdotal case have been reported lung adenocarcinoma could occasionally transform into small cell carcinoma. Most of the reported cases were EGFR-mutant lung adenocarcinomas that transform into small cell carcinoma during EGFR tyrosine kinase inhibitor treatment. However, some cases also indicate lu...
EGAS00001001757 | EGA
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Genomicsena-DATASET-KAIST-03-05-2017-03:08:17:539-449 - samples
This dataset includes the high-throughput sequencing data from a study entitled "Clonal History and Genetic Predictors of Transformation into Small Cell Carcinomas from Lung Adenocarcinomas". Whole-genome sequencing libraries were generated by PCR-free methods, and sequencing run was made in HiSeq X ...
EGAD00001003315 | EGA
1K
OtherKorea Advanced Institute of Science and Technology
Organisation EGAO00000000900
EGAO00000000900 | EGA
0
GenomicsData access committee (DAC) in the Graduate School of Medical Science and Engineering (GSMSE) at Korea Advanced Institute of Science and Technology (KAIST)
Data Access Committee EGAC00001000587
EGAC00001000587 | EGA
1K
OtherKAIST
Organisation EGAO00000000716
EGAO00000000716 | EGA
0
TranscriptomicsGenome-wide consequences of compromised NMD and their relavence for variable clinical phenotype of patients with UPF3B mutations [mRNA profiling]
Nonsense-mediated mRNA decay (NMD) surveillance pathways are best known to be involved in the degradation of mRNA with premature termination codons (PTCs). More recent studies demonstrate that the role of NMD pathways goes well beyond the degradation of PTC containing mRNA, into the regulation of cel...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-27125 | biostudies-arrayexpress
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