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ProteomicsExpression of glycan receptors for influenza A viruses in mallards, chickens, and tufted ducks
...demics result from interspecies transmission events within the avian reservoir and further into mammals including humans. Investigating the molecular basis for virus–host interactions enabling this process is vital to understand zoonotic IAV spread. Receptor incompatibility has been suggested to limi...
ORGANISM(S): Gallus Gallus (chicken) 
2024-04-18 | PXD036263 | Pride
Glycoproteomics Adaptive viral mutations Mallard Influenza virus : interspecies transmission Innate immunity Sialic acid receptor Tufted duck 
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ProteomicsProtein Expression in TW Formation
...oping secondary xylem, sections were then pooled to represent the tissues from specific developmental stages. Phloem (P) comprises 3 sections, the cambium (C) - 2 sections, the radial expansion zone (E) - 4 sections, the first to third xylem development zones (X1-X3) - 3 sections each, and the forth ...
ORGANISM(S): Populus Tremula 
2017-06-23 | PXD005715 | Pride
Lc-ms Populus Tension wood 
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ProteomicsRegulatory Role of S100A6 in Hematopoetic Stem Cells
The fate options of hematopoietic stem cells (HSCs) include self-renewal, differentiation, migration and apoptosis, but the interaction between intracellular Ca2+ and cytoplasmic chaperon protein in regulating fate options of long term-HSCs (LT-HSC) is unknown. We created a S100A6 conditional knockou...
ORGANISM(S): Mus Musculus (mouse) 
2020-06-22 | PXD015854 | Pride
Mouse Hematopoetic stem cell Lc-ms/ms 
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ProteomicsmiR-126 Governs Human Leukemia Stem Cell Quiescence and Therapeutic Resistance
...ole in disease progression and recurrence due to their intrinsic capacity for self-renewal and chemotherapy resistance. Whereas epigenetic mechanisms balance normal blood stem cell self-renewal and fate decisions, mutation and dysregulation of epigenetic regulators are considered fundamental to leuke...
ORGANISM(S): Homo Sapiens (human) 
2016-03-31 | PXD001994 | Pride
Aml Stem cells Scx Global proteomics Mir126 
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GenomicsGenome-wide mapping of DEK binding in the U937 cell line
We find that the DEK oncoprotein preferentially binds close to the transcription start sites of highly and ubiquitously expressed genes. Sequencing of DNA precipitated by an antibofy against the DEK oncoprotein (ChIP-seq).
ORGANISM(S): Homo sapiens 
2014-09-26 | E-GEOD-60692 | biostudies-arrayexpress
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TranscriptomicsRNA-seq of coding RNA from tissue samples of 122 human individuals representing 32 different tissues
...RNA-seq was performed of tissue samples from 122 human individuals representing 32 different tissues in order to study the human tissue transcriptome. This submission contains 27 new samples and the data from E-MTAB-1733. This dataset is part of the TransQST collection.
ORGANISM(S): Homo sapiens 
2015-01-14 | E-MTAB-2836 | biostudies-arrayexpress
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Genomics,MultiomicsFramingham Cohort

<b>Startup of Framingham Heart Study. Cardiovascular disease (CVD) is the leading cause of death and serious illness in the United States. In 1948, the Framingham Heart Study (FHS) -- under the direction of the National Heart Institute (now known as the National Heart, Lung, and Blood Institut...

phs000007.v17.p6 | EGA
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TranscriptomicsThe Stockholm Atherosclerosis Gene Expression (STAGE) study: Global Gene Expression data from coronary and carotid artery disease patients
Tissue samples have been isolated during corornary artery by-pass grafting (CABG)surgery from the atheroscelrotic arterial wall (AAW, aortic root puncture for proxmal ligation of by-pass vessel), non-atherosclertoci arterial wall (NAAW, distal part of mammary artery used a graft for LAD), liver, ske...
ORGANISM(S): Homo sapiens 
2012-08-21 | E-GEOD-40231 | biostudies-arrayexpress
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TranscriptomicsHPA RNA-seq normal tissues
RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes. This dataset is part of the TransQST collection.
ORGANISM(S): Homo sapiens 
2013-12-06 | E-MTAB-1733 | biostudies-arrayexpress
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