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ProteomicsPattern Analysis of Organellar Maps for Interpretation of Pro-teomic Data
The human proton-coupled folate transporter (PCFT) was stably expressed as a fu-sion protein with a BioID2-HA in the C-terminal position (PCFT-BioID2). The uncom-plxed biotin transferase was used as a control to identify proteins that are biotinylated randomly due to sheer abundance and/or an unnatur...
ORGANISM(S): Homo Sapiens (human) 
2022-06-09 | PXD032297 | Pride
pattern analysis Proteomics  pattern analysis  bioinformatics  proximity labeling proximity labeling Proteomics bioinformatics 
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ProteomicsPlastoglobules are a biosynthetic platform contributing to carotenoid accumulation during tomato fruit maturation
Chloroplasts and chromoplasts of tomato fruits contain lipid droplets known as plastoglobules (PG). Recent studies have shown that PG act as a metabolic sink to store ...
... chromoplast PG with known PG proteins. Interestingly, most of the carotenoid biosynthetic pathway enzymes such as PSY‐1, PDS, ZDS, CRTISO, and β‐LYC are enriched in chromoplast PG compared with chloroplast PG. In this study, we propose a model of chromoplast PG acting as a carotenoid biosynthesis platform.
ORGANISM(S): Solanum Lycopersicum 
2023-03-11 | PXD035763 | Pride
Plastoglobules Lc-msms Chromoplasts Proteome Tomato Carotenoid 
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ProteomicsImmunological Sexual Dimorphism in Placenta and Its Response to Benzene Exposure
...arding the adverse effects of air pollution on human health, and benzene is a major toxic compound in air pollution. Maternal benzene exposure has been associated with reproductive complications, such as preterm birth, low birth weight, and immunological and neurological complications in the offsprin...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-20 | PXD035085 | Pride
Pregnancy Placenta Maternal immune activation Benzene exposure Sexual dimorphism 
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Proteomics,MultiomicsComprehensive protein profiling of tomato phloem exudates during drought stress and recovery
Phloem is the primary conduit through which photosynthates, hormones, and other biologically important molecules are distributed from aerial plant organs downward and throughout the plant. Increasing evidence suggests that phloem contents are diverse and play a critical role in biotic and abiotic stre...
ORGANISM(S): Solanum Lycopersicum 
2020-06-26 | PXD018993 | Pride
Phloem exudate Exudate Phloem Abiotic stress Tomato Drought 
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TranscriptomicsTranscription profiling of human squamous cell carcinomas to predict response to neoadjuvant chemoradiotherapy in oesophageal cancer patients
To use gene expression profiles to predict response to neoadjuvant chemoradiotherapy in oesophageal cancer patients.
ORGANISM(S): Homo sapiens 
2008-02-08 | E-MEXP-426 | biostudies-arrayexpress
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TranscriptomicsTranscription profiling of S. pneumonia early response to to THP-1 human macrophages
Transcriptional responses of an unencapsulated Streptococcus pneumoniae strain derived from TIGR4 to human macrophages THP-1 were investigated at the early stages of interactions (0.5 h, 1 h and 3h).
ORGANISM(S): Streptococcus pneumoniae 
2008-10-21 | E-FPMI-16 | biostudies-arrayexpress
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TranscriptomicsTranscription profiling of Streptococcus pneumoniae after incubation with host respiratory tract epithelial cells
In order to study pneumococcal gene expression changes after incubation with host epithelial cells, logarithmic-phase grown S. pneumoniae strains (82 and R6) were incubated with host epithelial cells (A549 and ETEC) in T75 cell culture flasks at an MOI range of 10:1 ~ 50:1. After incubation for 1 h o...
ORGANISM(S): Streptococcus pneumoniae 
2008-05-07 | E-TABM-187 | biostudies-arrayexpress
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TranscriptomicsTranscription profiling of Streptococcus pneumoniae TCS08 mutant (disrupted in rr08) compared to the parent wild type strain TIGR4
Transcriptional changes of an TCS08 mutant (disrupted in rr08) compared to the parent wild-type strain TIGR4 when both strains were cultured to early logarithmic growth phase in THY broth.
ORGANISM(S): Streptococcus pneumoniae 
2008-12-20 | E-FPMI-17 | biostudies-arrayexpress
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TranscriptomicsComparison of salt stress resistance genes in transgenic Arabidopsis thaliana indicates that extent of transcriptomic change may not predict secondary phenotypic or fitness effects
...productivity.There are concerns, however, regarding possible ecological impacts of transgenic crops. In contrast to the first wave of transgenic crops, many abiotic stress resistance genes can initiate complex downstream changes. Transcriptome profiling has been suggested as a comprehensive non-targe...
ORGANISM(S): Arabidopsis thaliana 
2011-10-05 | E-GEOD-26983 | biostudies-arrayexpress
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TranscriptomicsARR (Adamantyl Retinoid Related molecules)-miRNA-Cancer
The adamantly-substituted retinoid related (ARR) molecules have been found to induce apoptosis in a variety of malignant cells both in vitro and in vivo. A number of mechanisms have been proposed by which apoptosis is achieved by this class of molecules. We have previously demonstrated that ARRs are ...
ORGANISM(S): Homo sapiens 
2015-06-30 | E-MTAB-1482 | biostudies-arrayexpress
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