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Proteomicshuman nk cell line LC-MSMS - Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma
To identify protein binding partners of wild-type or Gαq T96S mutants using immunoprecipitation coupled to mass spectrometry.
ORGANISM(S): Homo Sapiens (human) 
2019-09-25 | PXD013285 | Pride
Human Lc-msms Nk cell line 
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ProteomicsLarge-scale Identification and Time-course Quantification of Ubiquitylomes in De-etiolating Maize Seedling Leaf
Ubiquitylation is a widely known post-translational modification that regulates myriad biochemical and physiological events in organism. The ubiquitin system is crucial for the development and fitness of higher plants. The process of de-etiolation, during which green plants initiate photomorphogenesis...
ORGANISM(S): Zea Mays (maize) 
2020-04-09 | PXD007880 | Pride
De-etiolation Ribosome Ubiquitylation Maize seedling leaf C4 photosynthetic enzymes 
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Proteomicsrat myocardial left ventricular tissue proteins LC-MSMS
...Da) were applied as isobaric tags for relative quantification. Then the labeled peptide aliquots were combined for fractionation and further LC-MS analysis. The LC–MS/MS analysis was carried out in Capitbalbio Technology by using Q Exactive mass spectrometer (Thermo Fisher Scientific, USA). Twenty mos...
ORGANISM(S): Rattus Norvegicus (rat) 
2021-07-26 | PXD024641 | Pride
Heart Lc-msms Rat 
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ProteomicsMultidimensional Molecular Characteristics of Early-Onset Endometrioid Endometrial Carcinoma, And Potential Predictors Of Response To Fertility Sparing Therapy
Endometrial carcinoma (EC) remains a public health concern with a growing incidence particularly in younger women. Women with early-onset endometrioid EC (EEEC) who wish to maintain fertility are a worldwide concern. To illuminate the molecular characteristics of EEEC, we undertook a large-scale multi...
ORGANISM(S): Homo Sapiens (human) 
2024-04-05 | PXD046507 | Pride
siglec10 Endometrial carcinoma  early-onset  carcinogen signature  fertility-sparing treatment  siglec10 early-onset Endometrial carcinoma carcinogen signature fertility-sparing treatment 
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ProteomicsGlobal crotonylatome and function analysis of lysine-crotonylated proteins in wheat response to cold stress
Abstract Lysine crotonylation (Kcr) is a recently identified post-translational modification (PTM) in the prokaryotic and eukaryotic organisms. However, the function of lysine-crotonylated proteins in response to abiotic stress in plants remains largely unknown. Here, we report the first global profil...
ORGANISM(S): Triticum Aestivum (wheat) 
2023-07-20 | PXD030768 | Pride
Crotonylatome tapgk ros Crotonylatome  cold stress  common wheat  tapgk  ros cold stress common wheat 
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ProteomicsMultiomics analysis of a DNAH5-mutated PCD organoid model revealed the key role of the TGF-β/BMP and Notch pathways in epithelial differentiation and the immune response in DNAH5-mutated patients
...ealed the genetic characteristics and pathogenetic mechanisms of PCD caused by DNAH5 mutation. Here, we established a child PCD airway organoid directly from the bronchoscopic biopsy of a patient with DNAH5 mutation. We found abnormal ciliary function and a decreased immune response caused by DNAH5 mu...
ORGANISM(S): Homo Sapiens (human) 
2023-03-11 | PXD038024 | Pride
Multiomics analysis Immune response Primary ciliary dyskinesia Dnah5 Airway organoid 
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ProteomicsCrotonylome profiling reveals extensive lysine crotonylation in common wheat
Histone lysine crotonylation (Kcr) is a newly discovered protein post-translational modification (PTM), which was detected from yeast to humans and is mainly related with active transcription. With the development of proteomics technologies, high abundance of non-histone proteins modified by Kcr was a...
ORGANISM(S): Triticum Aestivum (wheat) 
2023-07-20 | PXD008483 | Pride
lysine crotonylation proteomics Triticum aestivum l. mass spectrometry post-translational modification Triticum aestivum l.  post-translational modification  lysine crotonylation  proteomics  mass spectrometry 
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ProteomicsPlasma exosomal proteomic pattern in Hemophagocyticlymphohistiocytosis of a twin boy
Background: Secondary HLH is closely related to EBV infection, protein changes in plasma exosomes may be related to the pathogenesis of HLH patient. In recent years quantitative proteomic has been used to clarify the relationship between basic medicine and clinical medicine. Methods: Exosomes were iso...
ORGANISM(S): Homo Sapiens (human) 
2022-05-19 | PXD019088 | Pride
Hemophagocyticlymphohistiocytosis  twins exosomes proteomic analysis 
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GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cell ...

phs000361.v1.p1 | EGA
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GenomicsBLUEPRINT EpiVar 450K DNA methylation profiles of naive CD4+ T-cells, monocytes & neutrophils
BLUEPRINT EpiVar 450K DNA methylation profiles of naive CD4+ T-cells, > monocytes & neutrophils
EGAS00001001456 | EGA
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