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E-GEOD-2116

ABSTRACT: Transcription profiling of rat left ventricular samples from 12-, 16- and 20-month old spontaneously hypertensive rats (SHRs) compared with age-matched Wistar-Kyoto (WKY) rats as controls

OTHER RELATED OMICS DATASETS IN: PRJNA91775

PROVIDER: E-GEOD-2116 | ExpressionAtlas | 2014-08-15

REPOSITORIES: ExpressionAtlas

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Dataset's files

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			Action	DRS
	E-GEOD-2116-analysis-methods.tsv	Tabular
	E-GEOD-2116-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-2116-configuration.xml	Xml
	E-GEOD-2116-percentile-ranks.tsv	Tabular
	E-GEOD-2116.condensed-sdrf.tsv	Tabular

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SHR-WKY

Project description:Left ventricular gene expression profiles from 12-, 16- and 20-months old spontaneously hypertensive rats (SHRs) were compared with left ventricular profiles seen in age-matched Wistar-Kyoto (WKY) rats by screening Affymetrix U34A arrays (there are 4 samples in each timepoint except 3 samples of 20-months old WKYs). Keywords: time-course

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Transcription profiling of rat left ventricular samples from 12-, 16- and 20-month old spontaneously hypertensive rats (SHRs) compared with age-matched Wistar-Kyoto (WKY) rats as controls

Project description:Left ventricular gene expression profiles from 12-, 16- and 20-months old spontaneously hypertensive rats (SHRs) were compared with left ventricular profiles seen in age-matched Wistar-Kyoto (WKY) rats [control rats] by screening Affymetrix U34A arrays (there are 4 samples in each timepoint except 3 samples of 20-months old WKYs).

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Project description:Left ventricle gene expression was analyzed in three models of hypertension in order to clarify the molecular mechanisms associated with left ventricular hypertrophy. Transgenic heterozygous TGR(mRen2)27 rats, overexpressing the mouse renin gene, and their littermate negative controls, spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY), and Lyon hypertensive rats (LH) and their normotensive controls (LL) were included in the study.

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Transcription profiling of rat adrenal glands from spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto animals

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