Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-MTAB-6460

ABSTRACT: RNA-seq of heart left ventricle during myocardial ischemia in TAB-1 knock-in mice compared to wild type controls

PROVIDER: E-MTAB-6460 | ExpressionAtlas | 2018-09-17

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-MTAB-6460-analysis-methods.tsv	Tabular
	E-MTAB-6460-analytics.tsv	Tabular
	E-MTAB-6460-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-6460-configuration.xml	Xml
	E-MTAB-6460-g2_g1-mvaPlot.png	Other

Items per page:

1 - 5 of 21

Similar Datasets

Transcriptomic profiling of chronic infarcted pig hearts

Project description:Myocardial infarction (MI) is the leading cause for hear failure (HF). Following MI, the non-infarcted region of left ventricle (LV) is critical for maintaining heart function, and disruption of the LV contributes greatly to post-MI HF. Transcriptomic profiling by high-throughput sequencing was performed in a chronic HF pig model, to explore the molecular changes in the post-MI LV related to cardiovascular deterioration. Samples were taken from heart tissue of MI-induced pigs and from control pigs not subjected to MI. Regions of the heart where samples were taken included the site of ischemia (LV ischemia), area bordering ischemia (LV border), area remote to ischemia (LV remote) and the right ventricle (RV).

2021-10-04 | E-MTAB-8856 | biostudies-arrayexpress

E-MTAB-2561

Project description:myocardial infarction in Reg3beta knock-out mice

2015-07-27 | E-MTAB-2561 | ExpressionAtlas

E-MTAB-7595

Project description:RNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.

2019-08-07 | E-MTAB-7595 | ExpressionAtlas

Integrative proteomic and phosphoproteomics analysis of human ischemic and dilated cardiomyopathic explant tissues identifies etiology-specific phosphorylation patterns and signaling pathways

Project description:Myocardial tissue samples were explanted from the explanted left ventricle of heart failure patients with DCM (n=4), left ventricular infarct, peri-, and non-infarct regions of HF patients with ICM (n=4) at the time of their heart transplant surgeries, and the left ventricle of age- and sex-matched non-failing controls (NFC, n=4). Comparative quantitative analysis was performed on three independent sets (DCM vs. NFC, infarct vs. non-infarct, and peri- vs. non-infarct) labeled with 10-plex tandem mass tags. Following enrichment of phosphorylated peptides, the flow-through and eluted fractions were collected separately and subjected to LC-MS/MS (liquid chromatography-tandem mass spectrometry) on a Q-Exactive HF for global proteomics and phosphoproteomics profiling respectively.

2023-11-20 | PXD012664 | Pride

Transcription profiling of models of cardiac remodelling: myocardial infarction or transverse aortic constriction in left ventricle free wall and septum

Project description:We employed the Affymetrix GeneChip technology to evaluate the patterns of expression in two different in vivo models of cardiac remodeling and in two different regions (left ventricle free wall and septum) of the heart. Mice underwent transverse aortic constriction (TAC); myocardial infarction (MI) or Sham operation and RNA from the left ventricle free wall and the septum was isolated 1 week later.

2007-12-13 | E-GEOD-415 | biostudies-arrayexpress

RNA-seq of non-ischemic heart tissues treated with a traditional Chinese medicine formula (BYD) against myocardial ischemia in Sprague Dawley rats

Project description:The myocardial tissues of the ischemic left ventricle and the peri-ischemic rim (an approximately 1 mm rim of normal-appearing tissues) were removed, and the remaining tissues that consisted of non-ischemic left ventricle were obtained for the transcriptional analysis. The total RNA was extracted from the myocardia from the sham (n = 3), myocardial ischemia model (n = 3), and a traditional Chinese medicine formula treated on myocardial ischemia (n = 3) groups. Beads that contained oligo were used to isolate the poly mRNA from the total RNA and then the rRNA was subsequently removed. The amplified library was sequenced on a HiSeq 2500 sequencing machine (Illumina, San Diego, California, USA) with a 50 bp SE strategy. Using CASAVA software, the images generated by the Illumina sequencers were converted into raw reads by base-calling.

2019-02-04 | E-MTAB-6509 | biostudies-arrayexpress

E-GEOD-26887

Project description:Transcription profiling by array of left ventricle biopsies from diabetic and non diabetic patients affected by post-ischemic heart failure against samples from healthy controls

2025-01-24 | E-GEOD-26887 | ExpressionAtlas

E-MTAB-7291

Project description:RNA-seq of primary mouse monocytes from miR-150 knockout and Tet3 knockout mice compared to wild type controls

2019-01-16 | E-MTAB-7291 | ExpressionAtlas

E-MTAB-7221

Project description:Global transcriptomic profiles of blood monocytes from Hmox1 homozygous knockout mice compared to wild type controls following Mtb infection

2020-01-28 | E-MTAB-7221 | ExpressionAtlas

E-MTAB-6639

Project description:RNA-seq of mouse crypts to investigate Rorc gamma t-deficient mice tissue repair compared to wild type controls

2018-09-17 | E-MTAB-6639 | ExpressionAtlas