Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Doris Stoffers
PROVIDER: E-CBIL-5 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
De León Diva D DD Farzad Cyrus C Crutchlow Michael F MF Brestelli John J Tobias John J Kaestner Klaus H KH Stoffers Doris A DA
Physiological genomics 20060101 2
After partial pancreatectomy (Ppx), substantial regeneration of the endocrine and exocrine pancreatic compartments has been shown in adult rodents. Exendin-4 (Ex-4) is a glucagon-like peptide-1 receptor agonist that augments endocrine beta-cell mass by stimulating neogenesis, proliferation, and cell survival. After Ppx, treatment with Ex-4 ameliorates hyperglycemia by stimulating beta-cell mass recovery. We utilized a cDNA microarray approach to identify genes differentially regulated during pan ...[more]