Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Susanna Nikolaus
PROVIDER: E-GEOD-10108 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Schulze H A HA Häsler R R Mah N N Lu T T Nikolaus S S Costello C M CM Schreiber S S
Genes and immunity 20080313 3
Crohn's disease (CD) and ulcerative colitis (UC) are subforms of inflammatory bowel diseases (IBD). Genetic and environmental factors influencing the onset and course of the diseases have been recently identified. This study uses a two-step approach to detect genes involved in the pathogenesis of IBD by microarray analysis and real-time PCR (RT-PCR). In a first step, microarray expression screening was used to obtain tumour necrosis factor-alpha (TNF-alpha) induction profiles of two human cell l ...[more]