Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Sabrina Kuttruff
PROVIDER: E-GEOD-10178 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Kuttruff Sabrina S Koch Sven S Kelp Alexandra A Pawelec Graham G Rammensee Hans-Georg HG Steinle Alexander A
Blood 20081015 2
NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release. Recently, we demonstrated that the ligand for NKp80 is the myeloid-specific CTLR activation-induced C-type lectin (AICL), which is encoded in the natural killer gene complex (NKC) adjacent to NKp80. Here, we show that NKp80 also is expressed on a minor fraction of human CD8 T cells that exhibit a high responsi ...[more]