Dataset Information
Wounded vs unwounded hemocyte deficient embryos
Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Mark Winfield
PROVIDER: E-GEOD-10209 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos.
EMBO reports 20080314 5
By using a microarray screen to compare gene responses after sterile laser wounding of wild-type and 'macrophageless' serpent mutant Drosophila embryos, we show the wound-induced programmes that are independent of a pathogenic response and distinguish which of the genes are macrophage dependent. The evolutionarily conserved nature of this response is highlighted by our finding that one such new inflammation-associated gene, growth arrest and DNA damage-inducible gene 45 (GADD45), is upregulated ...[more]
