Dataset Information
Transcription profiling of human HeLa cells overexpressing hsa-mir-26b and hsa-mir-98 (super series)
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Vincenzo Alessandro Gennarino
PROVIDER: E-GEOD-12100 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
MicroRNA target prediction by expression analysis of host genes.
Genome research 20081216 3
MicroRNAs (miRNAs) are small noncoding RNAs that control gene expression by inducing RNA cleavage or translational inhibition. Most human miRNAs are intragenic and are transcribed as part of their hosting transcription units. We hypothesized that the expression profiles of miRNA host genes and of their targets are inversely correlated and devised a novel procedure, HOCTAR (host gene oppositely correlated targets), which ranks predicted miRNA target genes based on their anti-correlated expression ...[more]
