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Transcription profiling of temporal expression patterns in rat hippocampi of hypoxia tolerant and sensitive animals analyzed 0, 1, 3, 12, 24, and 48 hours after ischemia operation


ABSTRACT: Comparison of time-series gene expression pattern in hippocampus of hypoxia tolerant or sensitive rats. At 12 time-points ({0h, 1h, 3h, 12h, 24h, 48h} x 2) after ischemia operation, microdissected CA1 regions of the two groups were respectively subjected to oligonucleotide-based microarray analysis. MIAME information can be obtained at the web link.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Makoto Kano 

PROVIDER: E-GEOD-1357 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

A meta-clustering analysis indicates distinct pattern alteration between two series of gene expression profiles for induced ischemic tolerance in rats.

Kano Makoto M   Tsutsumi Shuichi S   Kawahara Nobutaka N   Wang Yan Y   Mukasa Akitake A   Kirino Takaaki T   Aburatani Hiroyuki H  

Physiological genomics 20050215 2


We have developed a visualization methodology, called a "cluster overlap distribution map" (CODM), for comparing the clustering results of time series gene expression profiles generated under two different conditions. Although various clustering algorithms for gene expression data have been proposed, there are few effective methods to compare clustering results for different conditions. With CODM, the utilization of three-dimensional space and color allows intuitive visualization of changes in c  ...[more]

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