MicroRNA and mRNA expression in human hepatitis C Virus liver biopsies
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Xinxia Peng
PROVIDER: E-GEOD-15387 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers.
Peng Xinxia X Li Yu Y Walters Kathie-Anne KA Rosenzweig Elizabeth R ER Lederer Sharon L SL Aicher Lauri D LD Proll Sean S Katze Michael G MG
BMC genomics 20090811
<h4>Background</h4>Hepatitis C virus (HCV) is a major cause of chronic liver disease by infecting over 170 million people worldwide. Recent studies have shown that microRNAs (miRNAs), a class of small non-coding regulatory RNAs, are involved in the regulation of HCV infection, but their functions have not been systematically studied. We propose an integrative strategy for identifying the miRNA-mRNA regulatory modules that are associated with HCV infection. This strategy combines paired expressio ...[more]
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