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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human BE(2)-C neuronal responses to WEEV infection

ABSTRACT: Human neuronal differentiation alters responsiveness to innate immune stimuli and virus infections. We used microarrays to examine the transcriptional responses of the human BE(2)-C neuroblastoma cell line to infection with western equine encephalitis virus (WEEV). Experiment Overall Design: Cultured BE(2)-C cells were differentiated with 10 uM all-trans retinoic acid (RA) for 3 weeks and infected with WEEV at an MOI=10 for 6 h, and Affymetrix Human Genome Array U133 Plus 2.0 chips were used to analyze transcript levels.

ORGANISM(S): Homo sapiens

SUBMITTER: David Miller

PROVIDER: E-GEOD-16451 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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