Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: X Shen
PROVIDER: E-GEOD-18555 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Falbo Karina B KB Alabert Constance C Katou Yuki Y Wu Su S Han Junhong J Wehr Tammy T Xiao Jing J He Xiangwei X Zhang Zhiguo Z Shi Yang Y Shirahige Katsu K Pasero Philippe P Shen Xuetong X
Nature structural & molecular biology 20091025 11
ATP-dependent chromatin remodeling complexes have been shown to participate in DNA replication in addition to transcription and DNA repair. However, the mechanisms of their involvement in DNA replication remain unclear. Here, we reveal a specific function of the yeast INO80 chromatin remodeling complex in the DNA damage tolerance pathways. Whereas INO80 is necessary for the resumption of replication at forks stalled by methyl methane sulfonate (MMS), it is not required for replication fork colla ...[more]