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Genome-wide mapping of Fos binding site (K562)

ABSTRACT: Proto-oncogene c-Fos is a leucine-zipper containing transcription factor which has a DNA binding domain and a transactivation domain. Fos dimerizes with another transcription factor Jun to form AP1 transcription factor. The AP-1 complex has been implicated in transformation and progression of cancer. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Map binding sites of transcription factor Fos in the genome of K562 cells. The K562 input data has been deposited in GEO as GSM325934.

ORGANISM(S): Homo sapiens

SUBMITTER: Michael Wilson

PROVIDER: E-GEOD-19546 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Close association of RNA polymerase II and many transcription factors with Pol III genes.

Raha Debasish D Wang Zhong Z Moqtaderi Zarmik Z Wu Linfeng L Zhong Guoneng G Gerstein Mark M Struhl Kevin K Snyder Michael M

Proceedings of the National Academy of Sciences of the United States of America 20100205 8

Transcription of the eukaryotic genomes is carried out by three distinct RNA polymerases I, II, and III, whereby each polymerase is thought to independently transcribe a distinct set of genes. To investigate a possible relationship of RNA polymerases II and III, we mapped their in vivo binding sites throughout the human genome by using ChIP-Seq in two different cell lines, GM12878 and K562 cells. Pol III was found to bind near many known genes as well as several previously unidentified target ge ...[more]

PMID: 20139302

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Genome-wide mapping of Jun binding site (K562)

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2009-12-31 | E-GEOD-19545 | biostudies-arrayexpress

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2009-12-31 | E-GEOD-19547 | biostudies-arrayexpress

Genome-wide mapping of RNA Polymerase II binding sites

Project description:Protein coding genes and some of the non-coding RNA genes in eucaryotes are transcribed by RNA Polymerase II. A transcription machinery complex consists of RNA Pol II and many other proteins including transcription factors, activators and repressors of transcription. Pol II binding sites are found in actively transcribing genes and many which are not actively transcribing. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Map binding sites of RNA Polymerase II in the genome of K562 & NB4 cells

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2009-12-31 | E-GEOD-19548 | biostudies-arrayexpress

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2008-09-15 | E-GEOD-12782 | biostudies-arrayexpress

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Genome-wide mapping of RNA Pol II binding site (GM12878)

Project description:We report the results of chromatin immunoprecipitation following by high-thoughput sequencing (ChIP-Seq) using the GA II platform from Illumina for the human RNA Polymerase II in GM12878 cells. We have also generated a sequenced input DNA datasets for GM12878 cells. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Map binding sites of RNA Polymerase II in the genome of GM12878 cells. The GM12878 input data has been deposited in GEO as GSM487430.

2009-12-31 | E-GEOD-19550 | biostudies-arrayexpress

Genome-wide mapping of RNA Pol III binding site (GM12878)

Project description:We report the results of chromatin immunoprecipitation following by high-thoughput sequencing (ChIP-Seq) using the GA II platform from Illumina for the human RNA Polymerase III in GM12878 cells. We have also generated a sequenced input DNA datasets for GM12878 cells. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Map binding sites of RNA Polymerase III in the genome of GM12878 cells.

2009-12-31 | E-GEOD-19549 | biostudies-arrayexpress

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