Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Gene expression comparisons of megakaryocyte-erythrocyte progenitors isolated from wild type and c-MybTG/c-MybTG mice


ABSTRACT: Transgene insertion in proximity to the c-Myb gene disrupts c-Myb expression in megakaryocyte-erythrocyte progenitors (MEPs), resulting in skewed commitment to megakaryocyte lineage. To understand the genes regulated by c-Myb at the megakaryocyte-erythrocyte bifurcation, MEPs of c-MybTG/c-MybTG mice were examined. Detailed analysis on c-MybTG/c-MybTG is descried in the paper by Mukai et al, Mol Cell Biol 2006. The IL-7R-Lin-Sca-1–c-Kit+ fraction was subdivided into FcR loCD34+, FcRloCD34-, and FcRhiCD34+ populations. Among them, FcRloCD34- fraction was use as MEPs. MEPs from 16 wild type mice and those from 32 c-MybTG/c-MybTG mice were pooled and used for RNA purification.

ORGANISM(S): Mus musculus

SUBMITTER: Hozumi Motohashi 

PROVIDER: E-GEOD-19901 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2011-01-10 | GSE19901 | GEO
2007-11-16 | E-GEOD-2031 | biostudies-arrayexpress
2015-06-15 | E-GEOD-62360 | biostudies-arrayexpress
2008-06-10 | GSE10593 | GEO
2022-11-19 | E-MTAB-11217 | biostudies-arrayexpress
2008-06-14 | E-GEOD-5677 | biostudies-arrayexpress
2019-04-16 | GSE113182 | GEO
2021-02-22 | GSE111410 | GEO
2010-06-26 | E-GEOD-10593 | biostudies-arrayexpress
| PRJNA323931 | ENA