Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptomes of Alveolar epithelial cells


ABSTRACT: Freshly isolated type I and type II alveolar epithelial cells were investigated for transcriptomes with dual-color DNA microarray using 3DNA 50 kit.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Lin Liu 

PROVIDER: E-GEOD-2160 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Alveolar type I cells protect rat lung epithelium from oxidative injury.

Chen Jiwang J   Chen Zhongming Z   Chintagari Narendranath Reddy NR   Bhaskaran Manoj M   Jin Nili N   Narasaraju Telugu T   Liu Lin L  

The Journal of physiology 20060501 Pt 3


The lung alveolar surface is covered by two morphologically and functionally distinct cells: alveolar epithelial cell types I and II (AEC I and II). The functions of AEC II, including surfactant release, cell differentiation and ion transport, have been extensively studied. However, relatively little is known regarding the physiological functions of AEC I. Global gene expression profiling of freshly isolated AEC I and II revealed that many genes were differentially expressed in AEC I. These gene  ...[more]

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