Gene expression profiles in AEC II during hyperoxia exposure and recovery
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Lin Liu
PROVIDER: E-GEOD-2707 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene expression of rat alveolar type II cells during hyperoxia exposure and early recovery.
Chen Zhongming Z Chintagari Narendranath Reddy NR Guo Yujie Y Bhaskaran Manoj M Chen Jiwang J Gao Li L Jin Nili N Weng Tingting T Liu Lin L
Free radical biology & medicine 20070531 4
Alveolar epithelial cell (AEC) injury and repair during hyperoxia exposure and recovery have been investigated for decades, but the molecular mechanisms of these processes are not clear. To identify potentially important genes involved in lung injury and repair, we studied the gene expression profiles of isolated AEC II from control, 48-h hyperoxia-exposed (>95% O(2)), and 1-7 day recovering rats using a DNA microarray containing 10,000 genes. Fifty genes showed significant differential expressi ...[more]
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