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Gene expression profiling of HUVEC under basal (resting) conditions

ABSTRACT: To understand the biological variability that exists between different individuals, the resting (untreated) transcriptome from 15 different individuals was examined. Transcripts expressed in a bimodal manor across the 15 biological replicates were identified for further examination. In the study presented here, HUVEC isolates from 15 different individuals were cultured until passage 4 in fully supplemented growth conditions. RNA was extracted and hybridised onto CodeLink microarrays. The expression profiles in the untreated condition were examined along side a subset of the same biological replicates treated with a cocktail of inflammatory mediators (10ng/ml TNF-α, Il-1β, Il-8) for a period of 24 hours prior to RNA extraction (also submitted).

ORGANISM(S): Homo sapiens

SUBMITTER: Muna Affara

PROVIDER: E-GEOD-23068 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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