Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Aquaporin-1 Knockout vs Wild type Mice (Re-spot found)

ABSTRACT: This dataset was derived (re-spot found) from the original images used in GSE1298. This experiment compared aRNA derived from the kidney inner medula of three mice lacking a functional aquaporin-1 gene to three wild type mice. Each sample was hybridized 4 times, against 4 of the other 5 samples, using an interwoven loop experimental design. Keywords: repeat sample

ORGANISM(S): Mus musculus

SUBMITTER: Heddwen Brooks

PROVIDER: E-GEOD-2402 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

CARMA: A platform for analyzing microarray datasets that incorporate replicate measures.

Greer Kevin A KA McReynolds Matthew R MR Brooks Heddwen L HL Hoying James B JB

BMC bioinformatics 20060317

<h4>Background</h4>The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust experimental design coupled with an analysis of variance (ANOVA) incorporating a model that accounts for known sources of experimental variability can significantly improve the determination of differences in gene expression and estimations of their significance.<h4>Results</h4>To realize the full benefits of perfo ...[more]

PMID: 16542461

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Dataset Information

Aquaporin-1 Knockout vs Wild type Mice (Re-spot found)

Publications

CARMA: A platform for analyzing microarray datasets that incorporate replicate measures.

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