Unknown,Transcriptomics,Genomics,Proteomics

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Human peripheral nervous system SAGE


ABSTRACT: expression profiles generated from sciatic nerve as well as from Schwann cells cultured thereof Keywords: other

ORGANISM(S): Homo sapiens

SUBMITTER: Anneloor ten Asbroek 

PROVIDER: E-GEOD-2529 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Transcriptional profile of the human peripheral nervous system by serial analysis of gene expression.

de Jonge Rosalein R RR   Vreijling Jeroen P JP   Meintjes Asker A   Kwa Marcel S G MS   van Kampen A H C AH   van Schaik Ivo N IN   Baas Frank F  

Genomics 20030801 2


The peripheral nerve contains both nonmyelinating and myelinating Schwann cells. The interactions between axons, surrounding myelin, and Schwann cells are thought to be important for the correct functioning of the nervous system. To get insight into the genes involved in human myelination and maintenance of the myelin sheath and nerve, we performed a serial analysis of gene expression of human sciatic nerve and cultured Schwann cells. In the sciatic nerve library, we found high expression of gen  ...[more]

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