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FVB nerve x SC comparison

ABSTRACT: wild-type mouse (FVB strain) expression profiles of adult sciatic nerve and of cultured Schwann cell Keywords: other

ORGANISM(S): Mus musculus

SUBMITTER: Anneloor ten Asbroek

PROVIDER: E-GEOD-2530 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Comparison of Schwann cell and sciatic nerve transcriptomes indicates that mouse is a valid model for the human peripheral nervous system.

Ten Asbroek Anneloor L M A AL Van Ruissen Fred F Ruijter Jan M JM Baas Frank F

Journal of neuroscience research 20060801 3

High-throughput gene expression analyses of murine models of the peripheral nervous system (PNS), and its cellular components, have yielded enormous amounts of expression data of the PNS in various conditions. These data provided clues for future research directions to further decipher this complex organ in relation to acquired and inherited PNS diseases. Various studies addressing the validity of mouse models for human conditions in other tissues and cell types have indicated that in many cases ...[more]

PMID: 16786575

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