Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: H Horvitz
PROVIDER: E-GEOD-2564 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lu Jun J Getz Gad G Miska Eric A EA Alvarez-Saavedra Ezequiel E Lamb Justin J Peck David D Sweet-Cordero Alejandro A Ebert Benjamin L BL Mak Raymond H RH Ferrando Adolfo A AA Downing James R JR Jacks Tyler T Horvitz H Robert HR Golub Todd R TR
Nature 20050601 7043
Recent work has revealed the existence of a class of small non-coding RNA species, known as microRNAs (miRNAs), which have critical functions across various biological processes. Here we use a new, bead-based flow cytometric miRNA expression profiling method to present a systematic expression analysis of 217 mammalian miRNAs from 334 samples, including multiple human cancers. The miRNA profiles are surprisingly informative, reflecting the developmental lineage and differentiation state of the tu ...[more]