Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Radha Duttagupta
PROVIDER: E-GEOD-27230 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
PloS one 20110617 6
Effective diagnosis and surveillance of complex multi-factorial disorders such as cancer can be improved by screening of easily accessible biomarkers. Highly stable cell free Circulating Nucleic Acids (CNA) present as both RNA and DNA species have been discovered in the blood and plasma of humans. Correlations between tumor-associated genomic/epigenetic/transcriptional changes and alterations in CNA levels are strong predictors of the utility of this biomarker class as promising clinical indicat ...[more]