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Gene expression analysis of interspecific and intraspecific Y chromosome introgessions in Drosophila simulans


ABSTRACT: These arrays measure gene expression across eight Y introgression lines in Drosophila simulans. Four lines (Ya19, Ya23, Ya24, Ya26) carry a D. simulans Y chromosome (from a Cameroon population) and four lines (Sec01, Sec03, Sec08, Sec27) carry a D. sechellia Y chromosome. All lines are otherwise identical with a D. simulans background (UCSD stock center line 14021-0251.092). Four biological replicates of each of eight lines, plus two technical replicates (dye swap), for a total of 32 arrays. Full methods are described in the accompanying publication.

ORGANISM(S): Drosophila simulans

SUBMITTER: Timothy Sackton 

PROVIDER: E-GEOD-31907 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Interspecific Y chromosome introgressions disrupt testis-specific gene expression and male reproductive phenotypes in Drosophila.

Sackton Timothy B TB   Montenegro Horacio H   Hartl Daniel L DL   Lemos Bernardo B  

Proceedings of the National Academy of Sciences of the United States of America 20111003 41


The Drosophila Y chromosome is a degenerated, heterochromatic chromosome with few functional genes. Nonetheless, natural variation on the Y chromosome in Drosophila melanogaster has substantial trans-acting effects on the regulation of X-linked and autosomal genes. However, the contribution of Y chromosome divergence to gene expression divergence between species is unknown. In this study, we constructed a series of Y chromosome introgression lines, in which Y chromosomes from either Drosophila s  ...[more]

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