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Mycobacterium avium subsp. paratuberculosis gene transcription in simulated phagosomal environment and in human macrophage infection

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE32241: Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro acid-nitrosative multi-stress GSE32242: Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line Refer to individual Series

ORGANISM(S): Mycobacterium avium subsp. paratuberculosis

SUBMITTER: Andrea Cossu

PROVIDER: E-GEOD-32243 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profiling of Mycobacterium avium subsp. paratuberculosis in simulated multi-stress conditions and within THP-1 cells reveals a new kind of interactive intramacrophage behaviour.

Cossu Andrea A Sechi Leonardo Antonio LA Zanetti Stefania S Rosu Valentina V

BMC microbiology 20120530

<h4>Background</h4>Recent studies have identified in Mycobacterium avium subsp. paratuberculosis (MAP), already known as a pathogen in ruminants, a potential zoonotic agent of some autoimmune diseases in humans. Therefore, considering the possible risk for public health, it is necessary a thorough understanding of MAP's gene expression during infection of human host as well as the identification of its immunogenic and/or virulence factors for the development of appropriate diagnostic and therape ...[more]

PMID: 22646160

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Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line

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2012-05-31 | E-GEOD-32241 | biostudies-arrayexpress

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2012-11-29 | E-GEOD-32236 | biostudies-arrayexpress

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2013-11-05 | E-GEOD-34623 | biostudies-arrayexpress

Signal Regulatory Protein Beta 2 is a novel positive regulator of innate anticancer immunity, GFP-IP/MS of SIRP-B2 on THP-1

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2023-12-04 | PXD047166 | Pride

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