Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: NIEHS Microarray Core
PROVIDER: E-GEOD-36267 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hesse Jill E JE Liu Liwen L Innes Cynthia L CL Cui Yuxia Y Palii Stela S SS Paules Richard S RS
PloS one 20130531 5
Deficiencies in the ATM gene are the underlying cause for ataxia telangiectasia, a syndrome characterized by neurological, motor and immunological defects, and a predisposition to cancer. MicroRNAs (miRNAs) are useful tools for cancer profiling and prediction of therapeutic responses to clinical regimens. We investigated the consequences of ATM deficiency on miRNA expression and associated gene expression in normal human mammary epithelial cells (HME-CCs). We identified 81 significantly differen ...[more]