Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Genome wide transcriptional profiling of HIV positive and negative children with active tuberculosis, latent TB infection and other diseases


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Victoria Wright 

PROVIDER: E-GEOD-39941 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


<h4>Background</h4>Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with the human immunodeficiency virus (HIV).<h4>Methods</h4>The study population comprised prospective cohorts of children who were undergoing evaluation for suspected tuberculosis in South Africa (655 children), Malawi (701 children  ...[more]

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