Ontology highlight
ABSTRACT:
ORGANISM(S): Arabidopsis thaliana
SUBMITTER: Shunping Yan
PROVIDER: E-GEOD-44793 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Yan Shunping S Wang Wei W Marqués Jorge J Mohan Rajinikanth R Saleh Abdelaty A Durrant Wendy E WE Song Junqi J Dong Xinnian X
Molecular cell 20131024 4
DNA damage is normally detrimental to living organisms. Here we show that it can also serve as a signal to promote immune responses in plants. We found that the plant immune hormone salicylic acid (SA) can trigger DNA damage in the absence of a genotoxic agent. The DNA damage sensor proteins RAD17 and ATR are required for effective immune responses. These sensor proteins are negatively regulated by a key immune regulator, SNI1 (suppressor of npr1-1, inducible 1), which we found is a subunit of t ...[more]