Transcription profiling of mouse strains (10) across 7 brain regions
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Jessica Nadler
PROVIDER: E-GEOD-5055 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype.
Nadler Jessica J JJ Zou Fei F Huang Hanwen H Moy Sheryl S SS Lauder Jean J Crawley Jacqueline N JN Threadgill David W DW Wright Fred A FA Magnuson Terry R TR
Genetics 20060915 3
Behaviors are often highly heritable, polygenic traits. To investigate molecular mediators of behavior, we analyzed gene expression patterns across seven brain regions (amygdala, basal ganglia, cerebellum, frontal cortex, hippocampus, cingulate cortex, and olfactory bulb) of 10 different inbred mouse strains (129S1/SvImJ, A/J, AKR/J, BALB/cByJ, BTBR T+ tf/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J, and FVB/NJ). Extensive variation was observed across both strain and brain region. These data provide po ...[more]
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