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HoxC11 ChIP-seq of LY2 Breast Cancer Cell Line

ABSTRACT: SRC-1 (NCOA1) is a steroid receptor coactivator that has been associated with various aspects of the progression of breast cancer disease such as tamoxifen resistance, metastasis, cell proliferation and invasiveness. In a tamoxifen resistant breast cancer cell line (LY2), SRC-1 has been found to interact with the developmental transcription factor HoxC11. ChIP-sequencing of HoxC11 in LY2 cells shows where the transcription factor binds throughout the genome. LY2 cells were treated with either tamoxifen or vehicle and immunoprecipitated with anti-Hoxc11

ORGANISM(S): Homo sapiens

SUBMITTER: Leonie Young

PROVIDER: E-GEOD-54027 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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