Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Kazumi Nakano
PROVIDER: E-GEOD-55851 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Clinical cancer research : an official journal of the American Association for Cancer Research 20140411 11
<h4>Purpose</h4>Cell adhesion molecule 1 (CADM1), initially identified as a tumor suppressor gene, has recently been reported to be ectopically expressed in primary adult T-cell leukemia-lymphoma (ATL) cells. We incorporated CADM1 into flow-cytometric analysis to reveal oncogenic mechanisms in human T-cell lymphotrophic virus type I (HTLV-I) infection by purifying cells from the intermediate stages of ATL development.<h4>Experimental design</h4>We isolated CADM1- and CD7-expressing peripheral bl ...[more]