Ontology highlight
ABSTRACT:
ORGANISM(S): Bacillus anthracis str. Ames
SUBMITTER: D Rasko
PROVIDER: E-GEOD-568 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hoffmaster Alex R AR Ravel Jacques J Rasko David A DA Chapman Gail D GD Chute Michael D MD Marston Chung K CK De Barun K BK Sacchi Claudio T CT Fitzgerald Collette C Mayer Leonard W LW Maiden Martin C J MC Priest Fergus G FG Barker Margaret M Jiang Lingxia L Cer Regina Z RZ Rilstone Jennifer J Peterson Scott N SN Weyant Robbin S RS Galloway Darrell R DR Read Timothy D TD Popovic Tanja T Fraser Claire M CM
Proceedings of the National Academy of Sciences of the United States of America 20040521 22
Bacillus anthracis is the etiologic agent of anthrax, an acute fatal disease among mammals. It was thought to differ from Bacillus cereus, an opportunistic pathogen and cause of food poisoning, by the presence of plasmids pXO1 and pXO2, which encode the lethal toxin complex and the poly-gamma-d-glutamic acid capsule, respectively. This work describes a non-B. anthracis isolate that possesses the anthrax toxin genes and is capable of causing a severe inhalation anthrax-like illness. Although init ...[more]