Ontology highlight
ABSTRACT:
ORGANISM(S): Bacillus anthracis
SUBMITTER: N Tourasse
PROVIDER: E-GEOD-341 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Read Timothy D TD Peterson Scott N SN Tourasse Nicolas N Baillie Les W LW Paulsen Ian T IT Nelson Karen E KE Tettelin Hervé H Fouts Derrick E DE Eisen Jonathan A JA Gill Steven R SR Holtzapple Erik K EK Okstad Ole Andreas OA Helgason Erlendur E Rilstone Jennifer J Wu Martin M Kolonay James F JF Beanan Maureen J MJ Dodson Robert J RJ Brinkac Lauren M LM Gwinn Michelle M DeBoy Robert T RT Madpu Ramana R Daugherty Sean C SC Durkin A Scott AS Haft Daniel H DH Nelson William C WC Peterson Jeremy D JD Pop Mihai M Khouri Hoda M HM Radune Diana D Benton Jonathan L JL Mahamoud Yasmin Y Jiang Lingxia L Hance Ioana R IR Weidman Janice F JF Berry Kristi J KJ Plaut Roger D RD Wolf Alex M AM Watkins Kisha L KL Nierman William C WC Hazen Alyson A Cline Robin R Redmond Caroline C Thwaite Joanne E JE White Owen O Salzberg Steven L SL Thomason Brendan B Friedlander Arthur M AM Koehler Theresa M TM Hanna Philip C PC Kolstø Anne-Brit AB Fraser Claire M CM
Nature 20030501 6935
Bacillus anthracis is an endospore-forming bacterium that causes inhalational anthrax. Key virulence genes are found on plasmids (extra-chromosomal, circular, double-stranded DNA molecules) pXO1 (ref. 2) and pXO2 (ref. 3). To identify additional genes that might contribute to virulence, we analysed the complete sequence of the chromosome of B. anthracis Ames (about 5.23 megabases). We found several chromosomally encoded proteins that may contribute to pathogenicity--including haemolysins, phosph ...[more]